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Predict the toxic endpoints of candidate compounds help select the most promissing candidates with ToxWiz
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Using ToxWiz you can predict toxic endpoits using compound structures. Our predictions are powered by systems biology and consider not only the compound structure, but how similar chemicals have been reported previously to affect biological systems. Through this process one has access to over a million curated relationships and documents.
You can also explore the mechanisms of action for structurally similar compounds, unraveling potential on and off-target compound effects and identifying genes or proteins potentially affected by your compounds. Ultimately this can help you to identify known and potential drug cross reactivities, and potential side effects.
Some features benefiting the medicinal chemist are:
- nearly 20 thousand chemicals linked to proteins, genes & toxic-endpoints
- the ability to go directly from a chemical or sub-structure search to possible protein targets or affected genes & pathways
- the possibility to combine chemical information quickly and seamlessly with data from biological sources, such as toxicogenomics or proteomics
- thousands of known chemical/protein interactions relevant to toxicology, including known ligands, substrates, products, inducers & supressors of all major drug metabolising enzymes, and nuclear hormone receptors
For more information contact us at info@camcellnet.com
To purchase the product contact our sales team sales@camcellnet.com
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It's cool! I think I could be inspecting these complexes all my life!
YeastWiz User Mark Brooks (University of Paris-Sud)
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Medicinal Chemists